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This report critically assesses the evidence that common and man-made chemicals widespread in the environment contribute to human male reproductive disorders. The disorders manifest themselves either at birth (malformation of the penis, undescended testicles) or in later in adulthood (reduced sperm count and quality or testicular cancer). The birth defects and later reproductive disorders share common risk factors and are considered as belonging to a testicular dysgenesis syndrome (TDS) with a common fetal origin. Written by Professor Richard Sharpe, Medical Research Council Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen’s Medical Research Unit, Edinburgh, UK.
The fully referenced report identifies important areas for further discussion not only within the male reproductive health and wider medical community but also within the circle of decision makers responsible for chemicals regulation.
This briefing highlights the trend of deteriorating male reproductive health and explores, via current peer-reviewed research, the links with hormone disrupting chemicals. The briefing outlines opportunities for improved chemicals policy to help prevent further deterioration of male reproductive health. It also provides a comprehensive list of chemicals that are associated with disruption of male reproductive development and the consumer products and food in which they are found.
This leaflet briefly describes the evidence that hormonally active chemicals may be implicated in the deterioration of male reproductive health, gives some statistics on the rates of malformation of the penis, undscended testicles, sperm counts and cancer of the testicle. Written for those affected and a wide public audience, the leaflet explains the hypothesis of testicular dysgenesis syndrome (TDS) and how all the above problems may be linked to exposure to these chemicals during a male baby’s pre-natal development. The leaflet also provides advice on what people can do to minimize their exposure.